Lumivive Wellness GLP-1 Program

Melanotan-1

Melanotan-1, also designated MT-1, afamelanotide, or [Nle4, D-Phe7]-alpha-MSH, is a synthetic linear analog of alpha-melanocyte-stimulating hormone (alpha-MSH). In clinical practice, Melanotan-1 is studied as a selective melanocortin-1 receptor (MC1R) agonist and as a tool compound for investigating the melanogenesis pathway and melanocortin-receptor signaling. Unlike the non-selective analog Melanotan-2, which engages multiple melanocortin receptors (MC1R through MC5R), the MT-1 clinical profile is weighted toward MC1R, the receptor most associated with melanin-synthesis pathways in preclinical models. Preclinical investigations have explored Melanotan-1 in experimental models studying: MC1R receptor binding and selectivity melanogenesis and melanin-synthesis pathways melanocyte signaling and gene-expression models photoprotection and UV-response studies melanocortin-receptor pharmacology and structure-activity relationships Mechanistic Insights: Experimental studies examine Melanotan-1 as an MC1R-selective melanocortin agonist, with downstream signaling studied primarily through the cyclic AMP (cAMP) pathway. Areas of investigation include: MC1R activation and cAMP signaling tyrosinase and melanin-synthesis enzyme pathways eumelanin production in melanocyte models receptor selectivity relative to MC3R, MC4R, and MC5R structure-activity relationships among alpha-MSH analogs These mechanisms are commonly studied in melanocyte cell cultures and receptor-binding assays. Compound Information Compound Name: Melanotan-1 (MT-1)Alternate Designations: Afamelanotide, [Nle4, D-Phe7]-alpha-MSH, NDP-MSHPeptide Class: Synthetic alpha-MSH Analog (Melanocortin Agonist)Sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2Molecular Formula: C78H111N21O19Molecular Weight: ~1646.9 g/molCAS Number: 75921-69-6 Product Specifications Purity: ≥99%Testing Methods: HPLC & Mass SpectrometryAppearance: Lyophilized white powderCAS Number: 75921-69-6 Each batch undergoes analytical verification to confirm peptide identity, purity, and consistency. Storage For optimal stability, store lyophilized peptides in a cool, dry environment away from direct light. Long-term storage conditions may vary depending on laboratory requirements. Prescribing Notice This compound is compounded by a licensed U.S. pharmacy and dispensed under prescription. Not intended for human consumption, therapeutic use, cosmetic use, or veterinary use.

$59.00